Anti-Androgen

ANTI ANDROGEN (Testosterone blocker)

Testosterone blockers, also known as anti-androgen drugs, are used to block the masculinizing effects of testosterone in transgender women. Aldactone (spironolactone) is most commonly used, but other drugs like Propecia (finasteride), Avodart (dutasteride), and Eulexin (flutamide) may also be prescribed.

What is the best anti-androgen for MTF?
  • Anti-androgen. Spironolactone 100 – 200 mg/day (up to 400 mg) Cyproterone acetatea 50–100mg/day. ...
  • Oral estrogen. Oral conjugated estrogens 2.5–7.5mg/day. Oral 17-beta estradiol 2–6mg/day.
  • Parenteral estrogen. Estradiol valerate 5–20mg i.m./2 weeks or cypionate 2–10mg i.m./week.
  • Transdermal estrogen.